Daily Synbiotic Monthly Refill

Clinical Trials

The majority of dietary supplements have never been tested in human clinical trials on the actual product.

DS-01® has been tested in multiple full formulation randomized, placebo-controlled clinical trials, including the largest probiotic clinical trial evaluating bloating, in otherwise healthy women and men.

In addition, DS-01®’s ingredients have been validated in clinical trials to assess benefits in and beyond the gut.

The Impact of Clinical Proof

Randomized, placebo-controlled trials provide clarity and bring rigor to scientific research for various reasons, including:

• Eliminate bias
• Rule out placebo-effect
• Establish causality
• Validate efficacy

By testing DS-01® as a full formulation, the entire product is validated for tolerability and efficacy.

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In Seed’s largest clinical trial on DS-01, 350 men and women were evaluated using clinically-validated GI endpoints in partnership with leading gastroenterology physicians and academic microbiome researchers. This study shows real-world relevance with participants from 40 states and territories, reflecting the broader US population.

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Bloating + Gas Relief*

• DS-01 resulted in a significant reduction in bloating and gas symptoms compared to placebo.

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Improvement in Regularity*

• DS-01 improved bowel habits, specifically addressing occasional constipation-related discomfort, stool quality, and supporting regularity compared to placebo.

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Reduced GI Discomfort*

• DS-01 led to a reduction in abdominal discomfort compared to placebo.

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Improved Quality of Life *

• DS-01 improved GI-related quality of life compared to placebo. This included greater food enjoyment, reduced food avoidance, and significantly less disruption of physical activity due to digestive events

Strains + Ingredients

DS-01® is formulated with 24 scientifically and clinically studied probiotic strains and a patented, non-fermenting prebiotic.

53.6 billion AFU. No refrigeration required.

Strains

Probiotic Inner Capsule

Proprietary formulation consisting of 24 probiotic strains (53.6 billion AFU) validated through strain-specific research and tested for all 14 classes of allergens identified by the European Food Safety Authority (EFSA).

*Identical strain, formerly known as Bifidobacterium adolescentis SD-BA5-IT

Prebiotic Outer Capsule

Our prebiotic formulation consists of punicalagins concentrated from Indian pomegranate—biotransformed by gut microbes into powerful metabolites for human health.

Safety + Testing

DS-01® is held to a superior standard of quality and safety, undergoing 50+ checkpoints throughout the production process testing for purity, potency, and contaminants.

Supplement Facts